SEVERE SKIN DISEASE IN LUPUS ASSOCIATED WITH HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS: CASE REPORTS AND REVIEW OF THE LITERATURE

Severe skin disease in lupus associated with hemophagocytic lymphohistiocytosis: case reports and review of the literature

Abstract Background Hemophagocytic lymphohistiocytosis (HLH) is a severe clinical entity associated with high mortality in the adult population.HLH has been associated with infections, malignancy and autoimmune conditions such as Systemic Lupus Erythematosus (SLE), however this is often in flying cross soft shell jacket the context of a disease fla

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A network-based approach to integrate nutrient microenvironment in the prediction of synthetic lethality in cancer metabolism.

Synthetic Lethality (SL) is currently defined as a type of genetic interaction in which the loss of function of either of two genes individually has limited effect in cell viability but inactivation of both genes simultaneously leads to cell death.Given the profound genomic aberrations 5.7 procharger acquired by tumor cells, which can be systematic

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Development and Validation of Nomogram to Preoperatively Predict Intraoperative Cerebrospinal Fluid Leakage in Endoscopic Pituitary Surgery: A Retrospective Cohort Study

BackgroundPituitary adenomas (PAs) are the most common tumor of the sellar region.PA resection is the preferred treatment for patients with clear indications for surgery.Intraoperative cerebrospinal fluid (iCSF) leakage is a major complication of PA resection surgery.Risk factors for iCSF leakage have been studied previously, but a predictive nomog

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